Fifteen Years

Fifteen Years to Open Source

You can’t change an organization, states the rst rule of change management, unless that organization can be changed. More to the point: you can’t change an organization unless its structure lets you promulgate new policies, implement those policies, and assess their outcome. While this idea might seem self-evident, it has been the shoal on which many companies have foundered. It’s also the key ...

Eurosurveillance - fifteen years of serving Europe.

Empowering the Community for over Fifteen Years

Book Volume 2 XVIII International AIDS Conference July 18-23 2010 • Vienna, Austria

Adult herpes simplex encephalitis: fifteen years' experience.

INTRODUCTION Herpes simplex encephalitis (HSE) is the most frequent cause of sporadic necrotizing encephalitis in adults. The aim of this study is to describe the characteristics of HSE and the factors influencing its outcome. MATERIAL AND METHODS Retrospective study of patients diagnosed with HSE in a tertiary care teaching hospital over a 15-year period. Diagnosis was based on a consistent ...

Fifteen years of anti-HER2 therapy.

Last month brought the accelerated approval by the US Food and Drug Administration (FDA) of a fourth agent targeting the human epidermal growth factor receptor 2 (HER2) oncogene product: TDM-1 (Kadcyla), a conjugate of trastuzumab and a cytotoxic, emtansine. In a disease setting where once we had little to offer patients, we are now in a time of relative plenty, with a multitude of choices. It ...